Which word to choose?

Which word to use, and how to say it?

1

Ive never lost that many in succession. (this is off?)

Ive never lost that many by succession.

2

The biggest amount I've ever won was 10000 pounds.

The largest amount I've ever won was 10000 pounds.

3

100 people isn't a lot considering there are more than 100000 people here usually.

100 people isn't a lot if you take into account there are more than 100000 people here usually.

Thank you