Role of HMG-CoA Reductase Inhibitors in Neurological Disorders: Progress to Date Abstract: Inhibitors of HMG-CoA reductase (statins) are cholesterol-lowering agents that dramatically reduce morbidity and mortality in patients with established cardiovascular disease. In addition, they exhibit pleiotropic effects that operate independently of lipid modification. Statin administration results in greater nitric oxide bioavailability, improved endothelial function, enhanced cerebral blood flow, immune modulation with anti-inflammatory action, decreased platelet aggregation and antioxidant activity. Some or all of these effects may improve outcome or ameliorate symptoms in neurological disorders. This article examines the potential role of statins in treating stroke, Alzheimer's disease, multiple sclerosis and Parkinson's disease. Studies are ongoing in this controversial area, but there are no firm conclusions. The appropriateness of initiating statin therapy for neurological disorders is not established at this time. The exception is stroke, in which recurrence is significantly reduced by statin therapy.
Guess you guys read fast, so put the whole abstract here. The may in red is what I'm referring to. Does it mean 'is possible to' or 'can', my choice is the first, but don't know if it's right. Thanks in advance.
Top answer
Statin administration produces certain results. (five or six of them) Your author doesn't put any "maybe's" in the first link. But he puts a double maybe into the next link (as to whether they're beneficial in the treatment of the listed neurological disorders.
— Avangi
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Statin administration produces certain results. (five or six of them) Your author doesn't put any "maybe's" in the first link. But he puts a double maybe into the next link (as to whether they're beneficial in the treatment of the listed neurological disorders. Some or all of these five or six may - The "or" allows that perhaps #3 - or #5 - or both - have n
AvangiThe reason I say five or six effects is that I don't understand this phrase: << decreased platelet aggregation and antioxidant activity >> . Does he mean both are decreased, or only platelet aggregation?? (Is antioxidant activity increases or decreased?)
Thank you again, A. The first part of your reply makes me know how much attention I should pay when communicating with a native speaker. And I also see how precise English language is in this case. The two points are even more important than the question itself. I now no longer think I can post without making mistakes(misunderstanding) without the help of a dictionary. So next time I'll pu
"May" communicates the idea of possibility. "Can" carries the idea of possibility too, but because "Can' also is used to communicate ability - it conveys more certainty than "May".