IPod, iPhone, iPad, e-reader

Do we cap a brand name (like iPod, iPhone, iPad) when it starts a sentence? Ordinarily, it's spelled iPod, iPhone, and iPad. But when each word starts a sentence, do we change it to this?

This?
IPods, iPads, and iPhones are major technological breakthroughs from Apple.

Or this?
iPods, iPads, and iPhones are major technological breakthroughs from Apple.

It's a brand name. Should the "i" should be lowercase, even as the first letter in a sentence?

What about the brand name 'e-reader,' which is lowercase?
Would we uppercase or lowercase it at the beginning of a sentence as well?

This?
e-reader is a device that is used to display electronic books and other digital publications.

Or this?
E-reader is a device that is used to display electronic books and other digital publications.

In general, do we uppercase any brand name that is ordinarily lowercase by trademark when it starts a sentence?

Thanks.