{"id":27077,"date":"2019-12-04T20:00:45","date_gmt":"2019-12-04T20:00:45","guid":{"rendered":"https:\/\/www.englishforums.com\/news\/?p=27077"},"modified":"2019-12-04T20:00:45","modified_gmt":"2019-12-04T20:00:45","slug":"microfluidic-technology-cures-diseases","status":"publish","type":"post","link":"https:\/\/www.englishforward.com\/news\/microfluidic-technology-cures-diseases\/","title":{"rendered":"Microfluidic technology: A tool for studying complex diseases"},"content":{"rendered":"<p><strong><em><span data-preserver-spaces=\"true\">A Virginia Tech professor, along with his team of researchers discovered a new approach of using microfluidic technology.<\/span><\/em><\/strong><\/p>\n<h2><span data-preserver-spaces=\"true\">New microfluidic technology discovered<\/span><\/h2>\n<p><span data-preserver-spaces=\"true\"><a href=\"https:\/\/www.englishforums.com\/news\/vaping-deaths-diseases-a-new-epidemic\/\" target=\"_blank\" rel=\"noopener\">Little do we know about diseases and how our body reacts to their attacks<\/a>, the human DNA is a complex structure that makes every individual unique.<\/span><br \/>\n<span data-preserver-spaces=\"true\">But a Virginia Tech professor, together with his team of researchers, have developed a new technology that will help scientists understand how the human body reacts to certain diseases.<\/span><br \/>\n<span data-preserver-spaces=\"true\">Part of a recently published paper titled\u00a0<\/span><em><span data-preserver-spaces=\"true\">Nature Protocols,\u00a0<\/span><\/em><span data-preserver-spaces=\"true\">Chang Lu, a professor of Chemical Engineering at Virginia Tech, together with chemical engineering doctoral students Yuan Hsieh and Bohan Zhu, discussed the use of microfluidic technology to study various complex diseases such as Schizophrenia, cancer, and different kinds of addiction.<\/span><br \/>\n<span data-preserver-spaces=\"true\">According to Professor Lu:<\/span><\/p>\n<blockquote><p><em><span data-preserver-spaces=\"true\">We were motivated to pursue this research since the molecular basis of specific diseases remains elusive and unexplainable after years of research.<\/span><\/em><\/p><\/blockquote>\n<h2><span data-preserver-spaces=\"true\">MOWChIP-seq<\/span><\/h2>\n<p><span data-preserver-spaces=\"true\">The group of chemical engineers developed a technology which they refer to as\u00a0<\/span><a href=\"https:\/\/www.nature.com\/articles\/s41596-019-0223-x\" target=\"_blank\" rel=\"noopener\"><em><span data-preserver-spaces=\"true\">Microfluidic Oscillatory Washing-based Chromatin Immunoprecipitation followed by sequencing<\/span><\/em><\/a><span data-preserver-spaces=\"true\">\u00a0or\u00a0<\/span><strong><em><span data-preserver-spaces=\"true\">MOWChIP-seq<\/span><\/em><\/strong><span data-preserver-spaces=\"true\">.<\/span><br \/>\n<span data-preserver-spaces=\"true\">This model is considered unique and more convenient, compared to traditional methods which require tens of millions of cells per trial. The MOWChIP-seq is a low input technology which allows data processing of genomes by using as few as 100 cells per test.<\/span><br \/>\n<span data-preserver-spaces=\"true\">With the new method, the team can generate data of histone modifications using as few as 100 cells per trial with a result as accurate as eight trials in one run.<\/span><br \/>\n<span data-preserver-spaces=\"true\">According to Lu:<\/span><\/p>\n<blockquote><p><em><span data-preserver-spaces=\"true\">By comparing the DNA chemical process undergone between normal and diseased organisms, we can obtain useful marks and patterns which can be used to produce precision medicines.<\/span><\/em><\/p><\/blockquote>\n<p><span data-preserver-spaces=\"true\">What adds up to the success of this project is that it is semi-automated. It dramatically decreases manual labour error and improves reproducibility making it more scalable.<\/span><br \/>\n&nbsp;<br \/>\n&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A Virginia Tech professor, along with his team of researchers discovered a new approach of using microfluidic technology. New microfluidic technology discovered Little do we know about diseases and how our body reacts to their attacks, the human DNA is a complex structure that makes every individual unique. But a Virginia Tech professor, together with [&hellip;]<\/p>\n","protected":false},"author":21,"featured_media":27091,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[24,25],"tags":[],"_links":{"self":[{"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/posts\/27077"}],"collection":[{"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/users\/21"}],"replies":[{"embeddable":true,"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/comments?post=27077"}],"version-history":[{"count":0,"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/posts\/27077\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/media\/27091"}],"wp:attachment":[{"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/media?parent=27077"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/categories?post=27077"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.englishforward.com\/news\/wp-json\/wp\/v2\/tags?post=27077"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}